CD19 抗体
Quick Overview for CD19 抗体 (ABIN6936612)
抗原
See all CD19 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms.
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交叉反应 （详细）
- Human and Monkey.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human CD19 protein
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亚型
- IgG1 kappa
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anti-CD19 Molecule (CD19) (AA 151-250) antibody
CD19 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 20-291) antibodyCD19 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 8G11B7 unconjugated
anti-CD19 Molecule (CD19) (C-Term) antibodyCD19 适用: 人, 小鼠, 大鼠, 猴, 绵羊, Pig, Cow, 豚鼠, 兔, 犬, Avian, Cat, 小鸡, 驴, 山羊, Hamster, 马 WB 宿主: 山羊 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 485-556) antibodyCD19 适用: 人, 小鼠, 大鼠, 绵羊 FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (pTyr531) antibodyCD19 适用: 人, 小鼠 FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 96-281) antibodyCD19 适用: 人 FACS, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal CD19-3116 unconjugated
anti-CD19 Molecule (CD19) antibodyCD19 适用: 人 FACS, WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 143-172) antibodyCD19 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 160-258) antibodyCD19 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 20-291) antibodyCD19 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4C6G1 unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: hPBL or Raji cells. Human tonsil, lymph node or spleen.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD19 (CD19 Molecule (CD19))
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别名
- CD19
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背景
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B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CVID3, Leu-12, Lymphocyte Surface Antigen, T-cell surface antigen Leu-12,CD19 (B-Lymphocyte Marker)
Cellular localisation: Cell Surface -
分子量
- 95kDa
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基因ID
- 930, 652262
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UniProt
- P15391
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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